News and upcoming events


We are very pleased to announce the latest publication of the DIST pilot study group in Acta Neurochirugica (Wien):
Safety and technical efficacy of early minimally invasive endoscopy-guided surgery for intracerebral haemorrhage: the Dutch Intracerebral haemorrhage Surgery Trial pilot study | SpringerLink
In preparation of the Dutch ICH Surgery Trial, that already randomized its first patients, we engaged in ensuring the safety and technical efficacy of minimally invasive endoscopy guided surgery for intracerebral hemorrhage within 8 hours after symptom onset.
We need to progress our work within the DIST to determine whether this intervention also improves functional outcome of patients with this detrimental disease with its current high mortality and morbidity.


Last follow up is planned in April 2022. In the meanwhile, we are working on getting the DIST RCT up and running.


Inclusion has been closed. All ICH-patients that were admitted last weekend will be allowed to enter the study. Patients will not be included anymore starting 1st november 2021.


The countdown of inclusions has started. For the complete newsletter of October, click here.


Read our latest newsletter.


Only 2 surgical patients to go, we still need controls. For the complete newsletter of November 2020 (#12), click here.


At this point in time we’ve included 125 patients in the DIST-study. Of these 38 were in the surgical arm, so only 2 left to go! 


The stress around COVID seams to slow down a little, so far 114 patients are included. For the complete newsletter of September 2020 (#11), click here.


Inclusion rates are steadily growing with 35 chirurgical patients and 77 controls. For the complete newsletter of August 2020 (#10), click here.

02-07-2020 COVID-19 update

We are very pleased that all participating centers have restarted inclusion of patients in the DIST pilot study. This means that patients from hospitals nearby can also again be referred to Radboudumc, AMC or ErasmusMC for surgical treatment (of course after consultation of the concerning site).
For any questions, please contact us per e-mail or telephone (06- 11 19 69 11)


Inclusions in both surgical and control centers have bene resumed!
For the complete newsletter of July 2020 (#9), click here.


Due to COVID-19/SARS-CoV2 inclusion in most centers are set on hold.
For the complete newsletter of April 2020 (#8), click here.


Rinske Hoogland has started as our new research employee.
For the complete newsletter of February 2020 (#7), click here.


After summer, all sites made a great effort to include 11 new patients in September! For the complete newsletter of September click here.


It is been a year since the Medical Ethics Committee approval and 6 months since the first patient was included, and the first 3 patients are operated on. For the complete newsletter of May click here.


The first three patients in the DIST pilot study were operated on march 28th, march 30th and april 6th. For the complete newsletter of April, click here


Important changes are made in the study procedures. There are some changes in the (e)CRF, and the production server of OpenClinica is now in use (which means the sandbox server is closed). All patients will be transferred to the production server. For the complete newsletter of March, click here.


all centers are initiated, control patients are being included and we are waiting for the first surgical patient to operate him/her with the Artemis device.


On January 7th en 8th the neurosurgeons in the Radboudumc, Erasmus MC and AMC were trained in the use of the 2nd generation Artemis device. As soon as the devacied will be delivered, we can start operating patients! For the full newsletter of January, click here.


On November 27th, the first patiënt was included in the DIST pilot study! With this first inclusion, the DIST pilot study now has officially started. Seven of the ten centers are now initiated, and we expect to have initiated all 10 participating centers before the end of 2018. We are waiting for the Artemis device, to start the study in the surgical centers as well. For the full newsletter of December, click here.


Local Board of Directors approval in the Radboudumc: the pilot study has started!


The Medical Ethical Committee has given approval to start the study!